Arrhythmias & electrophysiology

Cost-effectiveness of an intraoperative antibacterial envelope in preventing cardiac implantable device-associated infections: a systematic review

EuropacePublished Systematic review of economic evaluations

Authors' conclusion

Routine use of an antibacterial envelope in patients undergoing CIED procedures (implantation or revision) is unlikely to be cost-effective except among those at high risk for post-operative infection.

Study context

Population
Patients undergoing cardiac implantable electronic device (CIED) procedures (implantation or revision); economic evaluations from high-income countries, healthcare payer perspective
Participants
7 studies
Comparison
Antibacterial envelope vs standard of care
Outcome
Cost-effectiveness (cost per quality-adjusted life year gained)
Methodological details142 unique citations screened
  • 142 unique citations screened

Pooled result

As reported in the abstract

Cost per quality-adjusted life year gained (base case)

Base case cost per QALY exceeded country-specific thresholds for good value

5/7

May be cost-effective at base infection rates greater than

3%

Cost-saving at infection rates exceeding

6%

Original publication

Cost-effectiveness of an intraoperative antibacterial envelope in preventing cardiac implantable device-associated infections: a systematic review. Europace. Published 16 June 2025. doi:10.1093/europace/euaf121

Summarised from the published abstract; every number is checked against it

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