Heart failure & cardiomyopathies

Cost-Utility Analysis of Add-On Qili Qiangxin Capsules in Chronic Heart Failure with Reduced Ejection Fraction in China

ESC Heart FailPublished cost-utility analysis

Authors' conclusion

This cost-utility analysis suggested that adding QLQX capsules seems to be cost-effective of heart failure with a reduced ejection fraction patients from the healthcare payer's perspective in China. Future studies of QLQX capsules based on different economic systems and medical environments were also needed.

Study context

Population
Patients with heart failure with a reduced ejection fraction in China
Comparison
Adding Qili Qiangxin (QLQX) capsules to standard treatment versus standard treatment
Outcome
Mean total costs
Follow-up
19-year lifetime horizon
Methodological detailsMarkov model, healthcare payer's perspective, 19-year lifetime horizon, 3-month cycle, discount rate of cost and utility 5%
  • Markov model
  • Healthcare payer's perspective
  • 19-year lifetime horizon
  • 3-month cycle
  • Discount rate of cost and utility 5%

Main finding

As reported in the abstract

Further findings

QALYs · 19-year lifetime horizon

Incremental cost-utility ratio (ICUR)

ICUR
57 381.85 CNY per QALY
Willingness-to-pay threshold
89 358 CNY
  • Lower than the willingness-to-pay threshold

Sensitivity analyses

Adding QLQX capsules to standard treatment was preferred over standard treatment alone in the 1000 PSA samples at a willingness-to-pay threshold of 89 358 CNY
51.10%
The one-way and probability sensitivity analyses showed that the results were robust
The inputs with the largest impact on ICUR were the cardiovascular mortality in both groups

Original publication

Cost-Utility Analysis of Add-On Qili Qiangxin Capsules in Chronic Heart Failure with Reduced Ejection Fraction in China. ESC Heart Fail. Published 11 March 2025. doi:10.1002/ehf2.15272

Composed by AI from the published abstract and checked against it. How Briefs are made →

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