Cardio-oncology & other

Decreased postpartum exercise capacity after a diagnosis of pre-eclampsia: Implications for CVD risk prediction

Am Heart JPublished Prospective observational cohort study

Authors' conclusion

Postpartum exercise stress testing capacity is related to readily available clinical markers including pregnancy factors, echocardiographic parameters and unresolved cardiometabolic risk factors.

Study context

Population
Postpartum women after normotensive or preeclamptic pregnancy
Participants
68 women
Exposure
Preeclampsia (PreE) with resolved vs persistent postpartum HTN vs normotensive pregnancy
  • Normotensiven = 15reference
  • PreE-Resolvedn = 36
  • PreE-HTNn = 17
Outcome
Postpartum exercise capacity (exercise duration, Bruce protocol stress testing)
Follow-up
12 weeks postpartum

Main finding

As reported in the abstract

Exercise duration (Bruce protocol stress testing)

P = 0.001

Observational data: associations, not effects.

Further findings

Postpartum weight loss

OutcomeNormotensivePreE-ResolvedPreE-HTN
Resting SBP112112134
Resting DBP70.072.585.0
Peak exercise lateral e'18.018.013.5
Peak exercise TR velocity (TR Vm)2.43.03.1
  • Resting systolic blood pressure (SBP): P < .001
  • Resting diastolic blood pressure (DBP): P < .001
  • Postpartum weight loss: P < .001
  • Peak exercise lateral e': P = .045
  • Peak exercise TR velocity (TR Vm): P = 0.045

Original publication

Decreased postpartum exercise capacity after a diagnosis of pre-eclampsia: Implications for CVD risk prediction. Am Heart J. Published 27 June 2024. doi:10.1016/j.ahj.2024.06.002

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