Arrhythmias & electrophysiology
Development and validation of a predictive model for atrial fibrillation recurrence post–catheter ablation in patients with nonvalvular atrial fibrillation on the basis of hemodynamic parameters
Authors' conclusion
Hemodynamic parameters may offer valuable insight into predicting AF recurrence after catheter ablation. Our study successfully developed a reliable nomogram on the basis of echocardiographic hemodynamic parameters to estimate the risk of AF recurrence after catheter ablation in patients with NVAF.
Study context
- Population
- Patients with nonvalvular atrial fibrillation (AF) (nonvalvular atrial fibrillation (NVAF)) undergoing AF catheter ablation132 (34.7%) with AF recurrence
- Participants
- 380 patients
- Outcome
- AF recurrence after catheter ablation
- Follow-up
- 1 and 2 years
Methodological detailsprediction model development and validation, consecutive patients, training and validation cohorts (7:3), nomogram, Mean follow-up 9 months, median 12 months
- Prediction model development and validation
- Consecutive patients
- Training and validation cohorts (7:3)
- Nomogram
- Mean follow-up 9 months, median 12 months
Main finding
As reported in the abstract
Hazard ratio (95% CI)P value
Persistent AF
1.63(1.02–2.61)
P = 0.041S/D ratio of pulmonary vein
0.50(0.30–0.84)
P = 0.009Left atrial acceleration factor α
1.31(1.02–1.68)
P = 0.032Left atrial appendage peak emptying flow velocity
0.98(0.97–0.99)
P = 0.004- Nomogram C index, 1-year AF recurrence (validation cohort)
- 0.664
- Nomogram C index, 2-year AF recurrence (validation cohort)
- 0.728
Observational data: associations, not effects.
Original publication
Development and validation of a predictive model for atrial fibrillation recurrence post–catheter ablation in patients with nonvalvular atrial fibrillation on the basis of hemodynamic parameters. Heart Rhythm. Published 3 September 2024. doi:10.
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