Prevention & lipidsCross-sectional study
Device-measured physical activity and cardiac structure by magnetic resonance
- Cross-sectional study
- UK Biobank
Authors' conclusion
High levels of device-measured physical activity were associated with cardiac remodelling within normal ranges.
Study context
- Population
- UK Biobank individuals without known CVD or hypertension; CMR 2015–2019; wrist-worn accelerometers
- Participants
- 5,977 vs 4,134
- Exposure
- Device-measured physical activity and CMR volumetric indices
- Womenn = 5,977
- Menn = 4,134
- Outcome
- LV end-diastolic volume indexed (LVEDVi) per additional 10 min/day of MVPA
Main finding
As reported in the abstract
LVEDVi per additional 10 min/day MVPA
Difference per 10 min/day MVPA, mL/m2 (95% CI)
Women
0.70(0.62–0.79)
Men
1.08(0.95–1.20)
Per additional 10 min/day MVPA, as printed
Observational data: associations, not effects.
Further findings
LVEDVi in top decile of MVPA (within normal ranges)
RV, atria, LVEF, left ventricular (LV) wall thickness, total PA and VPA
- Associations with MVPA also observed for RV and left/right atria
- Inverse association with LVEF
- Associations with maximum or average LV wall thickness not clinically meaningful
- Results for total PA and VPA mirrored those for MVPA
Original publication
Device-measured physical activity and cardiac structure by magnetic resonance. Eur Heart J. Published 14 August 2024. doi:10.1093/eurheartj/ehae506
Summarised from the published abstract; every number is checked against it