Myocardial Strain Measured by Cardiac Magnetic Resonance Predicts Cardiovascular Morbidity and Death
Authors' conclusion
In the general population, LV strain metrics derived using CMR-FT in radial, circumferential, and longitudinal directions are strongly and independently predictive of heart failure, myocardial infarction, and stroke, but only GLS is independently predictive of death in an adult population cohort.
Study context
- Population
- UK Biobank population imaging study participants (average age 65 ± 8 years)
- Participants
- 45,700 participants
- Exposure
- Lower vs higher absolute CMR-FT LV strain
- Outcome
- HF, MI, stroke and death
- Follow-up
- Median 3 years
Methodological detailspopulation imaging study, multivariable Cox models
- Population imaging study
- Multivariable Cox models
Main finding
As reported in the abstract
Only GLS independently predicted death: HR
1.18 (1.07-1.30) (95% CI)
Observational data: associations, not effects.
Original publication
Myocardial Strain Measured by Cardiac Magnetic Resonance Predicts Cardiovascular Morbidity and Death. J Am Coll Cardiol. Published 13 August 2024. doi:10.
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