Heart failure & cardiomyopathiesCohort study
Diabetes increases the risk of heart failure in myocarditis: a propensity-matched nationwide database analysis
- propensity-matched nationwide database analysis
- Multivariable logistic and Cox regression models
- propensity score matching was performed as a sensitivity analysis
Authors' conclusion
Diabetes independently increases the risk of in-hospital and one-year heart failure in patients with myocarditis.
Study context
- Population
- Adults hospitalized with a primary diagnosis of myocarditis, Nationwide Readmissions Database (2016–2020); those discharged alive followed for a calendar yearadults with myocarditis, 951 (11%) had diabetes
- Participants
- 8,826 adults
- Exposure
- Patients with diabetes vs patients without diabetes
- Diabetesn = 951
- Outcome
- In-hospital mortality
- Follow-up
- In-hospital
Main finding
As reported in the abstract
- No increased adjusted risk of mortality with diabetes
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Estimate | |
|---|---|---|
| In-hospital acute renal failure | aOR 1.74 (95% CI 1.42–2.12) | |
| In-hospital heart failure | aOR 1.62 (95% CI 1.37–1.91) | |
| In-hospital cardiogenic shock | aOR 1.36 (95% CI 1.04–1.78) | |
| One-year all-cause readmission | aHR 0.81 (95% CI 0.41–1.60) | |
| One-year mortality | aHR 0.81 (95% CI 0.68–0.97) | |
| One-year readmission for heart failure | aHR 1.16 (95% CI 1.02–1.31) | |
| 0.512Ratio (log scale) |
- One-year readmission for heart failure: These associations remained consistent in propensity score-matched analyses.
In-hospital ventricular fibrillation and ventricular tachycardia
- No increased adjusted risk with diabetes
Original publication
Diabetes increases the risk of heart failure in myocarditis: a propensity-matched nationwide database analysis. ESC Heart Fail. Published 23 February 2026. doi:10.1093/eschf/xvag064
Summarised from the published abstract; every number is checked against it