Diagnostic performance of a novel automated CT-derived FFR technology in detecting hemodynamically significant coronary artery stenoses: A multicenter trial in China
Authors' conclusion
The current study demonstrated esFFR had high diagnostic efficacy and fast processing speed in identifying hemodynamically significant CAD.
Study context
- Population
- Patients with coronary artery disease (CAD), 6 centres in China
- Participants
- 329 patients350 vessels
- Comparison
- esFFR vs coronary computed tomography angiography (CCTA), invasive FFR as reference standard
- Outcome
- Diagnostic performance in detecting hemodynamically significant lesions
Methodological detailsprospective, multicentre
- Prospective
- Multicentre
Performance
As reported in the abstract
| Test or model | Sensitivity, specificity, accuracy, PPV and NPV |
|---|---|
| esFFR | all above 90% |
esFFR
Sensitivity, specificity, accuracy, PPV and NPVall above 90%
Further findings
- esFFR processing speed
- 4.6 · average · ± 1.3 · minutes
Calcified lesions (post-hoc)
- Coronary calcification had minimal effects on esFFR's diagnostic performance
- Post-hoc analysis
"Gray zone" lesions (post-hoc)
- esFFR maintained diagnostic accuracy for "gray zone" lesions
- 85%
- Historical diagnostic accuracy for "gray zone" lesions
- <50%
- Post-hoc analysis
Original publication
Diagnostic performance of a novel automated CT-derived FFR technology in detecting hemodynamically significant coronary artery stenoses: A multicenter trial in China. Am Heart J. Published 21 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →