Arrhythmias & electrophysiology

Differences among young unwitnessed sudden cardiac death, according to time from last seen alive: Insights from a 15-year nationwide study

Heart RhythmPublished Nationwide retrospective cohort study

Authors' conclusion

The majority of unwitnessed SCD subjects had not been seen alive within 1 hour of being found dead. Clinical- and autopsy-related characteristics differed between the 2 groups.

Study context

Population
Unwitnessed SCD subjects aged 1–35 years in Denmark, 2000–2014
Participants
440 subjects
Exposure
Last seen alive 1–24 h vs <1 h before being found dead
  • 24-hourn = 366
Outcome
Clinical and autopsy characteristics by time from last seen alive to being found dead
Methodological detailsmultisource case identification, Denmark 2000-2014
  • Multisource case identification
  • Denmark 2000-2014

Main finding

As reported in the abstract

Not seen alive within 1 h of being found dead

Subjects not seen alive within 1 h of being found dead

366

83%

Observational data: associations, not effects.

Further findings

Comorbidities: epilepsy and psychiatric diseases

Epilepsy

Psychiatric diseases

Death during sleep, autopsy rate, unexplained after autopsy

Died during sleep

Autopsy rate

Unexplained after autopsy

OutcomeOR (95% CI)P value
Being autopsied (independent predictor, logistic regression)Seen within 1 h independently decreased chance of autopsy0.51 (0.27–1.00)P = 0.0497

Original publication

Differences among young unwitnessed sudden cardiac death, according to time from last seen alive: Insights from a 15-year nationwide study. Heart Rhythm. Published 14 July 2023. doi:10.1016/j.hrthm.2023.07.005

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