Arrhythmias & electrophysiology

Causes of sudden cardiac death according to age and sex in persons aged 1–49 years

Heart RhythmPublished Nationwide registry-based descriptive study

Authors' conclusion

The proportion of SCD cases that were identified with a potentially inherited cardiac disease postmortem was high in all studied age groups, while autopsy rates in sudden and unexpected death cases declined markedly with increasing age.

Study context

Population
All persons in Denmark aged 1–35 years (2000–2009) and 36–49 years (2007–2009); Sudden cardiac death (SCD) cases by 5-year age group27.1 million person-years
Outcome
Overall and sex-stratified causes of SCD according to age
Methodological detailsDenmark
  • Denmark

Main finding

As reported in the abstract

Causes of SCD by age group · 10-year study period

Deaths in study period

14,294

Classified as SCD

1362

10%

Potentially inherited cardiac disease among autopsied SCD, all age groups

43%-78%

SCD caused by sudden arrhythmic death syndrome, all age groups

19%-54%

Observational data: associations, not effects.

Further findings

Autopsy rates in sudden unexpected death and SCD cases

Autopsy rate, youngest age group
74%
Autopsy rate, oldest age group
35%
Declined significantly with increasing age

Original publication

Causes of sudden cardiac death according to age and sex in persons aged 1–49 years. Heart Rhythm. Published 6 September 2022. doi:10.1016/j.hrthm.2022.08.036

Composed by AI from the published abstract and checked against it. How Briefs are made →

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