Acute cardiac care & resuscitation
Differences Between Cardiogenic Shock Related to Acute Decompensated Heart Failure and Acute Myocardial Infarction
Authors' conclusion
ADHF-CS is characterized by a higher prevalence of end-organ and biventricular dysfunction at presentation, a longer hospital length of stay, and higher need of heart replacement therapies when compared with AMI-CS. In-hospital mortality was similar between the two aetiologies.
Study context
- Population
- Patients with cardiogenic shock in the Altshock-2 registry, March 2020–February 2022of 238 CS patients enrolled
- Participants
- 190 patients
- Exposure
- ADHF-CS vs AMI-CS
- ADHF-CSn = 89
- AMI-CSn = 101reference
- Outcome
- Characterization of ADHF-CS patients vs AMI-CS
Main finding
As reported in the abstract
Characteristics at presentation and management
Temporary mechanical support
P < 0.001
Heart transplantation
P < 0.01
LV assist device
0.01
| Outcome | AMI-CS | ADHF-CS | P value |
|---|---|---|---|
| Age | 67 (IQR 54-73) years | 63 (IQR 59-76) years | P = 0.01 |
| Creatinine | 1.2 (IQR 1.0-1.4) mg/dL | 1.6 (IQR 1.0-2.6) mg/dL | P < 0.001 |
| Bilirubin | 0.6 (IQR 0.4-1.1) mg/dL | 1.3 (IQR 0.9-2.3) mg/dL | P = 0.01 |
| Central venous pressure | 10 mmHg (IQR 7-14) | 14 mmHg (IQR 8-12) | P = 0.01 |
| Epinephrine use | — not stated in the abstract | 65.5% | |
| Norepinephrine use | 79.3% | — not stated in the abstract |
— not stated in the abstract
Observational data: associations, not effects.
Secondary outcomes
In-hospital mortality
P = 0.5
- In-hospital length of stay · longer in ADHF-CS
- P = 0.001
- In-hospital mortality: overall 41.1%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Differences Between Cardiogenic Shock Related to Acute Decompensated Heart Failure and Acute Myocardial Infarction. ESC Heart Fail. Published 18 September 2023. doi:10.
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