Pulmonary vascular disease & thromboembolism
Differential biventricular adaption to pulmonary vascular disease in patients with idiopathic/heritable and congenital heart disease: a prospective cardiac magnetic resonance and invasive study
Authors' conclusion
Despite comparable haemodynamic profiles, patients with post-operative PAH had less functional limitation than their IPAH/HPAH counterparts.
Study context
- Population
- Children with IPAH/HPAH or post-operative PAH
- Participants
- 64 children
- Exposure
- Post-operative PAH vs IPAH/HPAH
- Outcome
- Clinical status, haemodynamics and biventricular adaptation (cardiac magnetic resonance (CMR))
Methodological detailsconsecutive patients, age- and sex-matched healthy controls
- Consecutive patients
- Age- and sex-matched healthy controls
Main finding
As reported in the abstract
| Outcome | IPAH/HPAH | Post-operative PAH | P value |
|---|---|---|---|
| Clinical status, haemodynamics and biventricular adaptation (CMR) | 239 (SD 156) m | 320 (SD 193) m | |
| Functional class I/II | 26.3% | 61.5% | P = 0.02 |
- Post-operative PAH vs IPAH/HPAH: P = 0.008 — 6-min walk distance
- Post-operative PAH vs IPAH/HPAH: P < 0.05 — higher LV volumes and better RV function
Observational data: associations, not effects.
Original publication
Differential biventricular adaption to pulmonary vascular disease in patients with idiopathic/heritable and congenital heart disease: a prospective cardiac magnetic resonance and invasive study. Eur Heart J Cardiovasc Imaging. Published 18 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →