Heart failure & cardiomyopathies
Dilated Cardiomyopathy–Related Mortality in the United States: Demographic and Regional Trends Over the Past 2 Decades
Authors' conclusion
DCM-related mortality decreased over the past 2 decades, with a slight increase observed during the COVID-19 pandemic. Despite the decreasing trend, sex and racial disparities persisted, with men and Black people having the highest AAMR, whereas regional disparities changed, with the Midwest and South census regions showing an improvement compared with the West of the United States.
Study context
- Population
- US population >15 years with dilated cardiomyopathy (DCM)-related deaths, 2004–2022
- Participants
- 138,076 DCM-related deaths
- Outcome
- DCM-related AAMR per 100 000 people and annual percent changes
- Follow-up
- 2004 to 2022
Methodological detailsCDC WONDER database, Joinpoint regression
- CDC WONDER database
- Joinpoint regression
Main finding
As reported in the abstract
AAMR 2004
4.41
AAMR 2019
1.98
Average annual percentage change 2004–2019
−5.09
95% CI −5.40 to −4.86
AAMR 2021 (slight increase)
2.22
Observational data: associations, not effects.
Further findings
AAMR by sex
- Men consistently had 2- to 2.5-fold higher AAMR than women
AAMR by race and ethnicity
- Non-Hispanic Black people had the highest AAMR
AAMR by age group
- Highest mortality in age ≥75 years
AAMR by census region
- Midwest and South highest in 2004, overtaken by the West after 2010
AAMR by urbanization
- Rural and urban areas had similar age-adjusted mortality rates (AAMRs) for most years
Original publication
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