Heart failure & cardiomyopathies

Prognostic value of cardiac magnetic resonance–derived left ventricular filling pressure in non-ischemic cardiomyopathy

Eur Heart J Cardiovasc ImagingPublished retrospective

Main finding · Composite of all-cause mortality, heart transplantation, or hospitalization for heart failure (HHF)Result — go to the resultHazard ratio 2.11 95% CI 1.48–3.01

Authors' conclusion

CMR-modeled PCWP provides independent prognostic value providing further risk differentiation among patients traditionally classified as low-risk.

Study context

Population
Non-ischemic cardiomyopathy (NICM) patients who underwent cardiovascular magnetic resonance (CMR) between December 2008 and December 2017median follow-up 3.6 years
Participants
458 patients
Exposure
CMR-modeled pulmonary capillary wedge pressure (PCWP) ≥ 15 mmHg versus <15 mmHg
Outcome
Composite of:
  • All-cause mortality
  • Heart transplantation
  • Hospitalization for heart failure (HHF)
Follow-up
Median 3.6 years

Main finding

As reported in the abstract

Hazard ratio

2.11

95% CI 1.48–3.01

P < 0.001

By group

PCWP ≥ 15 mmHgvs PCWP of <15 mmHg
HR 2.11 (95% CI 1.48–3.01); P < 0.001

Observational data: associations, not effects.

Secondary outcomes

Baseline characteristics

Mean age
53.2 years
BMI
29.3 kg/m²
LVEF
32.8% ± 11.1%

Original publication

Prognostic value of cardiac magnetic resonance–derived left ventricular filling pressure in non-ischemic cardiomyopathy. Eur Heart J Cardiovasc Imaging. Published 30 December 2025. doi:10.1093/ehjci/jeaf353

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