Cardio-oncology & other

Disagreement between pharmacy claims and direct interview to identify patients with non-adherence to chronic cardiometabolic medications

Am Heart JPublished Secondary analysis of a randomised trial

Authors' conclusion

Among patients identified as non-adherent by claims, 39.6% were observed to be adherent when assessed during pharmacist consultation. This discrepancy was largely driven by paying out-of-pocket, using alternative insurance, or medication discontinuation or change.

Study context

Population
Patients with poorly controlled cardiometabolic disease identified as non-adherent by pharmacy claims
Participants
1,069 patients
Comparison
Pharmacist interview vs pharmacy claims (PDC <80%) to identify medication non-adherence
  • Agreementn = 646reference
  • Disagreementn = 423
Primary endpoint
Agreement of pharmacist assessment with claims-measured non-adherence

Primary result

As reported in the abstract

Pharmacist interview vs claims-based non-adherence (PDC <80%)

Further findings

OutcomeRR (95% CI)
Patient characteristics associated with disagreementDisagreementvs AgreementMissing outpatient office visits · multivariable modified Poisson regression0.91 (0.85–0.97)
Patient characteristics associated with disagreementDisagreementvs AgreementBaseline PDC above the median · multivariable modified Poisson regression1.35 (1.10–1.64)

Reasons for disagreement

Paying cash or alternate insurance
36.6%
Medication discontinuation or regimen change
32.8%
Recently becoming adherent
26.7%

Original publication

Disagreement between pharmacy claims and direct interview to identify patients with non-adherence to chronic cardiometabolic medications. Am Heart J. Published 28 October 2022. doi:10.1016/j.ahj.2022.10.083

Composed by AI from the published abstract and checked against it. How Briefs are made →

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