Coronary disease & ACS

Dynamic Coronary Roadmap versus standard angiography for percutaneous coronary intervention: the randomised, multicentre DCR4Contrast trial

EuroInterventionPublished Randomised controlled trial

Authors' conclusion

Compared to conventional angiography-guided PCI, DCR guidance was associated with a significant reduction in both contrast volume and the number of cineangiography runs during PCI.

Study context

Population
Patients undergoing percutaneous coronary interventions (PCI)randomised
Participants
356 patients
Comparison
Dynamic Coronary Roadmap (DCR)-guided PCI vs conventional angiography-guided PCI
  • DCRn = 179
  • Controln = 177reference
Primary endpoint
Total volume of iodinated contrast administered
Methodological detailsmulticentre, international, prospective, unblinded, stratified 1:1
  • Multicentre
  • International
  • Prospective
  • Unblinded
  • Stratified 1:1

Primary result

As reported in the abstract

Total contrast volume during PCI

P < 0.001

Secondary outcomes

OutcomeDCRControlP value
Number of cineangiography runs during PCI8.7 ± 4.711.7 ± 7.6P < 0.001

Original publication

Dynamic Coronary Roadmap versus standard angiography for percutaneous coronary intervention: the randomised, multicentre DCR4Contrast trial. EuroIntervention. Published 5 February 2024. doi:10.4244/eij-d-23-00460

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