Arrhythmias & electrophysiology
Early Rhythm Control in Patients With Incident Atrial Fibrillation Who Had a Prior Stroke
Main finding · Recurrent strokeResult — go to the resultWeighted hazard ratio 0.720 95% CI 0.666–0.779Authors' conclusion
Early rhythm control within 1 year after AF diagnosis might be beneficial to prevent recurrent stroke in patients with incident AF and a history of stroke.
Study context
- Population
- Patients newly diagnosed with atrial fibrillation (AF) and a history of prior stroke, Korean nationwide claims database; all prescribed OAC
- Participants
- 53,509 patients
- Exposure
- Early rhythm control vs usual care
- Early rhythm controln = 12,455
- Usual caren = 41,054reference
- Outcome
- Incident (recurrent) stroke
- Follow-up
- Median 2.6 years
Methodological detailspropensity score weighting, nationwide claims database
- Propensity score weighting
- Nationwide claims database
Main finding
Recurrent stroke · median 2.6 years
Weighted hazard ratio
0.720
95% CI 0.666–0.779
P < 0.001
Early rhythm controlvs Usual care
weighted HR 0.720 (95% CI 0.666–0.779); P < 0.001
As reported in the abstract
- Incident stroke, overall (4,382 patients)
- 2.6 per 100 person-years
Observational data: associations, not effects.
Original publication
Early Rhythm Control in Patients With Incident Atrial Fibrillation Who Had a Prior Stroke. JACC Clin Electrophysiol. Published 22 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →