Pulmonary vascular disease & thromboembolism
Echocardiographic Pressure–Strain Loop-Derived Stroke Work of the Right Ventricle: Validation Against the Gold Standard
Authors' conclusion
Integrated echo measurement of pressure-strain loop-derived SW correlates with PV loop-based assessment of RV SW. Wasted work correlates with invasive measures of load-independent RV function.
Study context
- Population
- Patients with PAH or chronic thromboembolic pulmonary hypertension (CTEPH) and patients without cardiopulmonary disease undergoing right ventricular (RV) echocardiography and invasive pressure-volume (PV) catheterization (EXERTION study)34 PAH/CTEPH, 8 controls
- Participants
- 42 patients
- Comparison
- Echo pressure-strain loop-derived RV stroke work vs invasive PV loop-derived RV stroke work
- Outcome
- Correlation of RVGWI with invasive PV loop-derived RV SW
Methodological detailsprospective
- Prospective
Performance
As reported in the abstract
RVGWI vs invasive RV SW correlation
Correlation, overall cohort (rho)
0.546
P < 0.001
Correlation, PAH/CTEPH subgroup (rho)
0.568
P < 0.001
Further findings
RV global wasted work (RVGWW) vs invasive elastance (Ea), Ees/Ea and Eed
- RVGWW correlated significantly with Ea, Ees/Ea and Eed
Original publication
Echocardiographic Pressure–Strain Loop-Derived Stroke Work of the Right Ventricle: Validation Against the Gold Standard. ESC Heart Fail. Published 6 July 2023. doi:10.
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