Heart failure & cardiomyopathies

Economic Burden of Heart Failure in Europe: A Systematic Review of Costs and Cost-Effectiveness

ESC Heart FailPublished Systematic review

Authors' conclusion

F imposes a substantial economic burden in Europe, largely driven by hospitalizations.

Study context

Population
Heart failure (HF) across European healthcare systems; studies published January 2000–January 202449 studies
Outcome
Economic impact of HF diagnosis, treatment and management

Pooled result

As reported in the abstract

Annual HF-related costs per patient, range across countries

€613 to €22,647

Hospitalizations: primary cost driver, share of total HF costs

15% to 92%

Further pooled results

Cost-effectiveness of HF therapies

ICERs of certain HF therapies, range
€1490 to €9406 per QALY gained

Cost-reduction strategies

Multidisciplinary care, telemonitoring and pharmacologic interventions; several disease management programmes reduced hospital admissions and ED visits

Original publication

Economic Burden of Heart Failure in Europe: A Systematic Review of Costs and Cost-Effectiveness. ESC Heart Fail. Published 26 November 2025. doi:10.1002/ehf2.70017

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