Heart failure & cardiomyopathies

Effect of 2022 American College of Cardiology (ACC)/American Heart Association (AHA)/Heart Failure Society of America (HFSA) Criteria on Stages of Heart Failure in a Pooled Community Cohort

J Am Coll CardiolPublished Pooled analysis of 3 longitudinal community cohort studies

An erratum to this article was published (J Am Coll Cardiol, 5 Sep 2023 ↗)

Authors' conclusion

New standards for HF staging resulted in a substantial shift of community-based individuals from stage A to stage B. Those with stage B HF in the new system were at high risk for progression to symptomatic HF.

Study context

Population
Community-based participants of MESA, CHS and FHS
Participants
11,618 participants
Comparison
2022 vs 2013 ACC/AHA/HFSA heart failure (HF) staging criteria
  • Healthyn = 1,943
  • Stage An = 4,348
  • Stage Bn = 5,019
  • Stage C/Dn = 308
Outcome
Prevalence and prognosis of HF stages by 2013 vs 2022 ACC/AHA/HFSA definitions
Methodological detailsMESA, CHS and FHS cohorts
  • MESA, CHS and FHS cohorts

Pooled result

As reported in the abstract

Prevalence of HF stages (2022 staging)
Stage B proportion, 2013 vs 2022 criteria
increase from 15.9% to 43.2%

Further pooled results

Progression to symptomatic HF, stage B (2022 criteria)

HR (95% CI)P value
Stage B10.61 (9.00–12.51)P < 0.001
  • Progression to symptomatic HF, stage B (2022 criteria): relative risk remained similar despite more individuals designated stage B

Original publication

Effect of 2022 ACC/AHA/HFSA Criteria on Stages of Heart Failure in a Pooled Community Cohort. J Am Coll Cardiol. Published 13 June 2023. doi:10.1016/j.jacc.2023.04.007

Composed by AI from the published abstract and checked against it. How Briefs are made →

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