Coronary disease & ACS

Effect of apixaban versus vitamin K antagonist and aspirin versus placebo on days alive and out of hospital: An analysis from AUGUSTUS

Am Heart JPublished Secondary analysis of the AUGUSTUS randomised trial

Authors' conclusion

In this analysis of AUGUSTUS, there was no difference in DAOH by treatment arm.

Study context

Population
Patients with AF and ACS or PCI
Participants
4,614 patients
Comparison
Apixaban vs warfarin and aspirin vs placebo
Primary endpoint
Days alive and out of hospital (DAOH)
Methodological detailsfactorial
  • Factorial

Primary result

As reported in the abstract

DAOH
Rate ratio for DAOH; no significant difference
Relative risk (95% CI)
Apixabanvs Warfarin
1.00(0.99–1.01)
Aspirinvs Placebo
1.00(1.00–1.01)

Further findings

OutcomeApixabanWarfarinOR (95% CI)
Neither died nor hospitalized during follow-up76.8 %73.3%0.83 (0.73–0.95)
  • Neither died nor hospitalized during follow-up: 75% of all patients neither died nor were hospitalized

Original publication

Effect of apixaban versus vitamin K antagonist and aspirin versus placebo on days alive and out of hospital: An analysis from AUGUSTUS. Am Heart J. Published 17 November 2024. doi:10.1016/j.ahj.2024.11.005

Composed by AI from the published abstract and checked against it. How Briefs are made →

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