Heart failure & cardiomyopathies
Effect of left bundle branch pacing on right ventricular function: A 3-dimensional echocardiography study
Authors' conclusion
LBBP induces excellent electrical and mechanical resynchronization, with a significant improvement in RV volumes and function. RVD did not diminish the beneficial effects on LV reverse remodeling after LBBP.
Study context
- Population
- Left bundle branch pacing (LBBP) candidates
- Participants
- 65 candidates
- Exposure
- LBBP in patients with RVD vs without RVD
- RVDn = 35
- No RVDn = 30reference
- Outcome
- LV reverse remodeling (reduction in LV end-systolic volume ≥15%)
- Follow-up
- 6-month follow-up
Main finding
As reported in the abstract
LV reverse remodeling
| Group | Value | Denominator |
|---|---|---|
| RVD | 29 events | 35 |
| No RVD | 27 events | 30 |
Value
RVD29 events
No RVD27 events
Denominator
RVD35
No RVD30
- RVD vs No RVD: P = 0.323 — similar
Observational data: associations, not effects.
Further findings
QRS duration, left ventricular (LV) size, LVEF, mechanical dyssynchrony · 6-month follow-up
- Significant reduction in QRS duration and LV size, and improvement in LVEF and mechanical dyssynchrony, in both No RVD and RVD
- P < 0.01
Right ventricular (RV) volumes and RVEF (RVD) · 6-month follow-up
- Significant improvement in RV volumes and RVEF in RVD
- P < 0.01
% reduction in QRS duration, LV dimensions, LV volumes; % improvement in LVEF · 6-month follow-up
- Similar in RVD and No RVD
- P＞.05
Original publication
Effect of left bundle branch pacing on right ventricular function: A 3-dimensional echocardiography study. Heart Rhythm. Published 24 December 2023. doi:10.
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