Heart failure & cardiomyopathies
Effects of Exercise Modalities on Physical Function and Quality of Life in Patients with Heart Failure: A Systematic Review and Network Meta-Analysis
Pooled result · Left ventricular ejection fractionResult — go to the resultMD 0.90 95% CI 0.42–1.38Authors' conclusion
Current evidence suggests that yoga, interval training, AT + RT, and HIIT + IMT significantly enhance physical function and quality of life in individuals with heart failure, with each modality exhibiting distinct advantages. Further high-quality studies are warranted to confirm these findings and refine exercise prescriptions for this population.
Study context
- Population
- Individuals with heart failure
- Participants
- 3,261 individuals60 randomized controlled trials
- Comparison
- Various exercise modalities on physical function and quality of life
- Outcome
- Left ventricular ejection fraction
Methodological detailsRandom-effects meta-analyses, searching PubMed, Embase and the Cochrane Library databases
- Random-effects meta-analyses
- Searching PubMed, Embase and the Cochrane Library databases
Pooled result
As reported in the abstract
MD
0.90
95% CI 0.42–1.38
Yoga
MD 0.90 (95% CI 0.42–1.38)
Further pooled results
Serum natriuretic peptide levels
| MD (95% CI) | ||
|---|---|---|
| YogaP-score = 0.965; most significant reduction | −1.46 (−1.88 to −1.04) | |
| −2−101Difference (linear scale) |
6-min walk distance (6MWD)
| MD (95% CI) | ||
|---|---|---|
| Interval trainingP-score = 0.873; superior effectiveness in increasing | 113.01 (28.55–197.47) | |
| −1000100200Difference (linear scale) |
Peak oxygen uptake (VO2peak)
| MD (95% CI) | ||
|---|---|---|
| AT + RTP-score = 0.829; greatest benefits | 3.68 (2.23–5.13) | |
| −50510Difference (linear scale) |
Quality of life
| MD (95% CI) | ||
|---|---|---|
| HIIT + IMTP-score = 0.871; most significant improvements | −19.28 (−26.42 to −12.14) | |
| −40−20020Difference (linear scale) |
Dyspnea
| MD (95% CI) | ||
|---|---|---|
| HIIT + IMTP-score = 0.804; greatest reduction | −1.58 (−2.64 to −0.52) | |
| −4−202Difference (linear scale) |
Original publication
Effects of Exercise Modalities on Physical Function and Quality of Life in Patients with Heart Failure: A Systematic Review and Network Meta-Analysis. ESC Heart Fail. Published 28 February 2025. doi:10.
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