Heart failure & cardiomyopathies

Effects of sauna bathing on exercise capacity and muscle function in heart failure with preserved ejection fraction (HFpEF) (SAUNA-HFpEF)

Eur J Heart FailPublished Mechanistic study

Authors' conclusion

Sauna bathing was safe, feasible, and improved exercise capacity, body composition, muscle function, and QoL in HFpEF. Benefits diminished after withdrawal.

Study context

Population
Stable HFpEF outpatientscompleted the study
Participants
18 outpatients
Comparison
Before vs after 10 weeks of supervised sauna bathing
Outcome
Peak VO2 and 6MWT, baseline to end of study (10 weeks)
Follow-up
10 weeks
Methodological detailsprospective, translational pilot study, single-group
  • Prospective
  • Translational pilot study
  • Single-group

Main finding

As reported in the abstract

10 weeks
Peak VO2 improved (ml/min/kg)
18.2±5.1 to 20.6±5.7 ml/min/kg, p<0.001
6MWT improved (m)
494±95 to 527±111m (p=0.006)
Anaerobic threshold, quadriceps strength, diastolic function (E/e´), HADS-depression-score and SF-36 social functioning also improved
p<0.05

Further findings

Anaerobic threshold, quadriceps strength, diastolic function (E/e´), HADS-depression score, SF-36 social functioning · 10 weeks

Improved
P < 0.05

Peak VO2 and anaerobic threshold at follow-up · 3 months after withdrawal

Declined compared to end of study
P < 0.01

Body fat mass

Decreased continuously

Muscle biopsies · 10 weeks

Anabolic/metabolic upregulation and catabolism downregulation

Safety

No adverse events
  • 97% adherence

Original publication

Effects of sauna bathing on exercise capacity and muscle function in HFpEF (SAUNA-HFpEF). Eur J Heart Fail. Published 14 March 2026. doi:10.1093/ejhf/xuag082

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