Heart failure & cardiomyopathies
Center- vs Home-Based Cardiac Rehabilitation in Patients With Heart Failure: EXIT-HF Randomized Controlled Trial
Authors' conclusion
In a contemporary well-treated HF population, home-based CR was noninferior to the center-based program
Study context
- Population
- Heart failure (HF) patients irrespective of EF95 (79%) with complete Vo2peak data
- Participants
- 120 patients
- Comparison
- Home-based vs centre-based cardiac rehabilitation
- Center-basedn = 45reference
- Home-basedn = 75
- Primary endpoint
- Change in peak oxygen uptake (Vo2peak)
- Follow-up
- 12 weeks
Methodological detailssingle-centre, parallel group, non-inferiority
- Single-centre
- Parallel group
- Non-inferiority
Primary result
As reported in the abstract
Change in Vo2peak from baseline to week 12
- No significant between-group difference in Vo2peak change (between-group difference 0.8 mL/kg/min, 95% CI 1.8 to −0.16 mL/kg/min)
- P = 0.10
Secondary outcomes
Exercise adherence to the CR program · similar between groups
6-minute walking distance, Minnesota Living with HF Questionnaire, disease-related biomarkers, physical fitness
- No between-group differences
Original publication
Center- vs Home-Based Cardiac Rehabilitation in Patients With Heart Failure: EXIT-HF Randomized Controlled Trial. JACC Heart Fail. Published 29 January 2025. doi:10.
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