Arrhythmias & electrophysiology
Efficacy and Safety of Adjunctive and Primary Use of the TightRail Mechanical Cutting Sheath for Lead Extraction
Authors' conclusion
Rotational cutting with TightRail was used in 42.8% of transvenous lead extractions, predominantly in an adjunctive manner after stalled laser progression in the innominate vein and superior vena cava, and more frequently for dual-coil and leads with longer dwell times. Adjunctive TightRail use carries a low risk of major complications.
Study context
- Population
- Patients undergoing transvenous lead extraction, April 2015 to January 2021251 (42.8%) with TightRail
- Participants
- 586 patients
- Outcome
- Utilization, safety and effectiveness of mechanical rotational cutting tools for transvenous lead extraction
Methodological detailssingle tertiary centre
- Single tertiary centre
Main finding
As reported in the abstract
Factors independently associated with adjunctive TightRail use (multivariable logistic regression)
TightRail
- Leads extracted
- 526
- TightRail used for leads
- 70.5%
- Adjunctive with laser (leads)
- 65.2%
- As second tool after stalled progression
- 97.8%
- Stalled progression in innominate vein and SVC
- 59.3%
TightRail
Leads extracted526
TightRail used for leads70.5%
Adjunctive with laser (leads)65.2%
As second tool after stalled progression97.8%
Stalled progression in innominate vein and SVC59.3%
Odds ratio (95% CI)P value
Active-fixation leads
2.78(1.62–4.78)
P = 0.0002Dual-coil leads
3.39(1.87–6.16)
P < 0.0001Lead dwell timeper 1-year increase
1.16(1.11–1.21)
P < 0.0001Per 1-year increase, as printed
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Clinical success | TightRail 96.8% |
Safety
| Outcome | Values |
|---|---|
| Major adverse events | TightRail 2.8% |
- Major adverse events — Major adverse events during TightRail use
- 1
Original publication
Efficacy and Safety of Adjunctive and Primary Use of the TightRail Mechanical Cutting Sheath for Lead Extraction. Circ Arrhythm Electrophysiol. Published 2 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →