Heart failure & cardiomyopathies
Electrical Resynchronization and Clinical Outcomes During Long-Term Follow-Up in Intraventricular Conduction Delay Patients Applied Left Bundle Branch Pacing-Optimized Cardiac Resynchronization Therapy
Authors' conclusion
LOT-CRT improves ventricular electrical synchrony and may provide greater clinical outcomes as compared with BiV-CRT in intraventricular conduction delay patients.
Study context
- Population
- Patients with intraventricular conduction delay and CRT indications
- Participants
- 30 vs 55
- Comparison
- LOT-CRT vs BiV-CRT
- LOT-CRTn = 30
- BiV-CRTn = 55reference
- Outcome
- QRS duration reduction
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
P < 0.001
Further findings
Implant success rate
LVEF · 6 months
P < 0.05
LVEF · 12 months
P < 0.05
LVEF · 18 months
P < 0.005
LVEF · 24 months
P < 0.05
| Outcome | HR | P value |
|---|---|---|
| Adverse clinical outcomes (HF rehospitalization and mortality) · 24 months | 0.33 | P = 0.035 |
Original publication
Electrical Resynchronization and Clinical Outcomes During Long-Term Follow-Up in Intraventricular Conduction Delay Patients Applied Left Bundle Branch Pacing-Optimized Cardiac Resynchronization Therapy. Circ Arrhythm Electrophysiol. Published 14 August 2023. doi:10. 1161/ circep. 122. 011761
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