Arrhythmias & electrophysiology
Electrocardiographic P terminal force in lead V1, its components, and the association with stroke and atrial fibrillation or flutter
Authors' conclusion
Abnormal PTFV1 was associated with an increased risk of AF and stroke/TIA. Increasing PTDV1 showed a dose-response relationship with the development of AF and stroke/TIA, whereas the association between PTAV1 and AF was less apparent.
Study context
- Population
- Patients with an electrocardiographic (ECG) recorded at the Copenhagen General Practitioners Laboratory, 2001–2011
- Participants
- 267,636 patients
- Exposure
- Abnormal P terminal force V1 (PTFV1) components and incident AF and stroke/TIA
- Abnormal PTFV1n = 44,549
- Outcome
- Incident AF and stroke/TIA
- Follow-up
- 6.5 years
Main finding
As reported in the abstract
Hazard ratio (95% CI)
Highest tertile of PTDV1AF
1.37(1.23–1.52)
Highest tertile of PTDV1stroke/TIA
1.13(1.05–1.20)
Highest tertile of PTAV1AF
1.20(1.09–1.32)
Highest tertile of PTAV1stroke/TIA
1.21(1.14–1.25)
Observational data: associations, not effects.
Further findings
Incident events in cohort · follow-up 6.5 years
- AF
- 5803
- Stroke/TIA
- 18,176
- Abnormal PTFV1 prevalence
- 16.7%
Original publication
Electrocardiographic P terminal force in lead V1, its components, and the association with stroke and atrial fibrillation or flutter. Heart Rhythm. Published 24 November 2022. doi:10.
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