Arrhythmias & electrophysiology
Ventricular rate in atrial fibrillation and the risk of heart failure and death
Authors' conclusion
Ventricular rates ≥100 bpm among patients presenting with AF on ECG in treatment with rate control drugs were associated with greater risk of both new-onset HF and all-cause mortality.
Study context
- Population
- Rate-control treated patients presenting with atrial fibrillation (AF) on electrocardiogram (ECG), Copenhagen General Practitioners Laboratory (2001–15)
- Participants
- 7,408 participants
- Exposure
- Ventricular rate categories on ECG vs 60-79 bpm
- Outcome
- New-onset diagnosed HF and all-cause mortality
- Follow-up
- 1 year
Main finding
As reported in the abstract
1-year follow-up
Each group vs 60-79 bpmHazard ratio (CI)
100-110 bpmnew-onset HF
1.46(1.10–1.95)
>110 bpmnew-onset HF
2.41(1.94–3.00)
100-110 bpmall-cause mortality
1.44(1.13–1.82)
>110 bpmall-cause mortality
1.34(1.08–1.65)
- All patients developing heart failure (HF)
- 666 (9.0%)
- All patients who died
- 858 (11.6%)
Observational data: associations, not effects.
Original publication
Ventricular rate in atrial fibrillation and the risk of heart failure and death. Europace. Published 21 April 2023. doi:10.
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