Arrhythmias & electrophysiology

P-wave terminal force in lead V1 and outcomes in patients with persistent atrial fibrillation undergoing catheter ablation

Am Heart JPublished Retrospective cohort study

Authors' conclusion

The PTFV1 at 3 months after AF ablation could be a valuable noninvasive predictor of both AF recurrence and cardiovascular events in patients with persistent AF.

Study context

Population
Patients with persistent atrial fibrillation (AF) undergoing first-time AF ablation453 examined
Participants
434 patients
Exposure
Abnormal vs normal PTFV1 at 3 months after AF ablation
  • Abnormal PTFn = 101
  • Normal PTFn = 333reference
Outcome
AF recurrence and composite CV events (stroke, HF hospitalization, CV death)
Follow-up
3 years
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

Abnormal PTF

AF recurrence
52.6%
CV events
13.7%

Normal PTF

AF recurrence
28.1%
CV events
2.6%

AF recurrence

Abnormal PTF52.6%
Normal PTF28.1%

CV events

Abnormal PTF13.7%
Normal PTF2.6%
Abnormal PTF vs Normal PTFHazard ratio (95% CI)P value
AF recurrence, adjusted; log-rank P < .001
2.12(1.44–3.13)
P < 0.001
CV events, adjusted; log-rank P = .005
3.26(1.19–8.97)
P = 0.022

Observational data: associations, not effects.

Original publication

P-wave terminal force in lead V1 and outcomes in patients with persistent atrial fibrillation undergoing catheter ablation. Am Heart J. Published 18 March 2023. doi:10.1016/j.ahj.2023.03.006

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