Arrhythmias & electrophysiology
Real-world evidence on the association between cardiac implantable electronic device infection and all-cause mortality
Main finding · All-cause mortalityResult — go to the resultAdjusted hazard ratio 2.73 95% CI 2.10–3.54Authors' conclusion
In a complete, state-wide cohort of CIED patients, infection was associated with higher risks of both short-term and long-term mortality.
Study context
- Population
- Patients aged >18 years undergoing a cardiac implantable electronic device (CIED) procedure, New South Wales, Australia, July 2017–September 20225,771 (15.3%) deaths
- Participants
- 37,750 patients
- Exposure
- CIED infection vs no infection
- CIED infectionn = 487
- Outcome
- All-cause mortality
- Follow-up
- 1 year and end
Methodological detailslinked hospital and mortality data, state-wide
- Linked hospital and mortality data
- State-wide
Main finding
As reported in the abstract
12 months post-procedure
Adjusted hazard ratio
2.73
95% CI 2.10–3.54
By group
CIED infectionvs No infection
aHR 2.73 (95% CI 2.10–3.54)
Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| All-cause mortality, end of follow-up · mean follow-up 25.2 (SD 16.8) monthsAttenuated but still significant | 1.83 (1.52–2.19) | |
| 0.512Adjusted hazard ratio (log scale) |
Original publication
Real-world evidence on the association between cardiac implantable electronic device infection and all-cause mortality. Europace. Published 13 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →