Arrhythmias & electrophysiology
Pleomorphism of premature ventricular complexes originating from papillary muscles and their myocardial connections
Authors' conclusion
VA pleomorphism in patients with PAP arrhythmias is most often due to premature ventricular complexes originating from different SOOs. The second most common cause is preferential conduction from a single SOO via PAP branching sites.
Study context
- Population
- Patients referred for ablation of focal LV papillary muscle (PAP) ventricular arrhythmias
- Participants
- 43 patients
- Outcome
- Prevalence and mechanisms of pleomorphic ventricular arrhythmias (PVAs)
Methodological detailsconsecutive patients, SOOs determined by activation and pacemapping
- Consecutive patients
- SOOs determined by activation and pacemapping
Main finding
As reported in the abstract
- Multiple VA morphologies
- n = 34 [79%]
- Multiple mechanisms generating the different VA morphologies
- 79%
- Among pleomorphic ventricular arrhythmias (PVAs): multiple SOOs from a single or different PAPs
- n = 23 [68%]
- Among PVAs: SOOs from PAP and non-PAP sites
- n = 19 [56%]
- Among PVAs: single SOOs accounted for PVAs
- 13 (38%)
Observational data: associations, not effects.
Further findings
Changing QRS morphologies after radiofrequency energy delivery targeting a single VA
- Patients with changing QRS morphologies
- 20
- Suggests a deeper focus with changing sites of preferential conduction
Original publication
Pleomorphism of premature ventricular complexes originating from papillary muscles and their myocardial connections. Heart Rhythm. Published 16 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →