Heart failure & cardiomyopathies
Epidemiology of Paediatric Chronic Heart Failure in Germany—A Population-Based Analysis
Authors' conclusion
This representative cohort study reveals a relatively high incidence proportion. Approximately half of the children with CHF are hospitalized annually while mortality is low.
Study context
- Population
- Individuals <18 years in a representative German claims database (InGef), 2016–2021; Chronic heart failure (CHF) defined by ≥2 diagnoses (ICD-10-GM I50.- or P29.0) in different quarters674,462 (2016)
- Outcome
- Prevalence and incidence of paediatric CHF per 100 000 children
- Follow-up
- 2016 and 2021
Methodological detailsretrospective, population-based, healthcare claims data (InGef database)
- Retrospective
- Population-based
- Healthcare claims data (InGef database)
Main finding
As reported in the abstract
Prevalence 2016, per 100 000
20.6
95% CI 17.3–24.3
Prevalence 2021, per 100 000
19.4
95% CI 16.2 to 23.0
Incidence of newly diagnosed CHF 2016, per 100 000
9.6
95% CI 7.4 to 12.3
Incidence of newly diagnosed CHF 2021, per 100 000
7.6
95% CI 5.6 to 10.0
Observational data: associations, not effects.
Further findings
Hospitalisation and mortality in children with CHF · per year
- All-cause hospitalisation per year
- 47.3% to 57.7%
- Hospitalised, coded primarily for HF
- Up to 6.3%
- Mortality, deaths per year
- <5
Most common ICD-coded comorbidities (128 children with CHF, 2021)
- Congenital malformations of cardiac septa
- 57.8%
- Atrial septal defect
- 44.5%
- Congenital malformations of the great arteries
- 43.0%
- Ventricular septal defect
- 32.0%
Coded treatment modalities · 2021
- ACEi or ARB
- 18.8%
- Beta-blockers
- 17.2%
- MRA
- 14.8%
- Surgical procedures
- 13.3%
Original publication
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