Evaluation of the Timing to Noncardiac Surgery following Cardiac Operations: A National Analysis
Main finding · MAEResult — go to the resultAdjusted odds ratio 0.69 95% CI 0.62–0.76Authors' conclusion
When feasible, delaying NCS, particularly beyond 100 days, appears to be associated with a reduction in adverse events, suggesting a potential opportunity for optimization of patient outcomes.
Study context
- Population
- Adults undergoing elective CABG, valve repair or replacement, or combined procedures, 2016 to 2020 Nationwide Readmissions Database, with subsequent admission for noncardiac surgery (NCS)patients undergoing cardiac surgery, 20,253 (1.5%) required a subsequent NCS
- Participants
- 1,335,175 adults
- Exposure
- Late NCS as compared to early NCS
- Outcome
- MAE
Methodological detailsrestricted cubic splines, risk-adjusted
- Restricted cubic splines
- Risk-adjusted
Main finding
As reported in the abstract
Adjusted odds ratio
0.69
95% CI 0.62–0.76
Late NCSvs Early NCS
adjusted OR 0.69 (95% CI 0.62–0.76)
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted OR (95% CI) | |
|---|---|---|
| In-hospital mortality | 0.66 (0.46–0.96) | |
| 0.512Adjusted odds ratio (log scale) |
Risk-adjusted MAE rates as a function of time delay after cardiac surgery
- Inflection point at days postoperatively
- 100
MAE after early NCS, by NCS risk and urgency
- Nonelective procedures classically categorized as low risk exhibited comparable rates of MAE to high-risk procedures following early NCS
Original publication
Evaluation of the Timing to Noncardiac Surgery following Cardiac Operations: A National Analysis. JACC Adv. Published 19 March 2025. doi:10.
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