Arrhythmias & electrophysiology

Excellent interobserver agreement and steep learning curve for target volume delineation for stereotactic arrhythmia radioablation using a commercial software

EuropacePublished Interobserver agreement study

Authors' conclusion

CardTV-EPinv creation showed excellent interobserver agreement and was faster and more robust using ADAS than 3D slicer.

Study context

Population
Patients considered for stereotactic arrhythmia radioablation (STAR) for ventricular tachycardia (VT)80 CardTV-EPinv created
Participants
20 patients
Comparison
ADAS vs Slicer3D workflows; experienced operator vs 2nd-year medical student
Outcome
Interobserver variability, ease of use and learning curve for EAM-based target volume (CardTV-EPinv) creation and transfer

Main finding

As reported in the abstract

Interobserver agreement (Hausdorff distance) with ADAS, 20 patients
HD between observers
1.68 mm [1.45-1.96]
95th percentile HD
< 4.8 mm [3.5-5.7]
CardTV-EPinv size, operator vs student
11.8 mL [10.1-13.7] vs. 10.7 mL [9.6-11.8], P = 0.17
Steep learning curve for the student (linear regression)
P = 0.01

Further findings

Workflow duration

P < 0.001

Events

OutcomeADASSlicer3D
System crashes07

Agreement between ADAS and Slicer3D workflows

HD
3.64 mm [2.7-4.5]

Original publication

Excellent interobserver agreement and steep learning curve for target volume delineation for stereotactic arrhythmia radioablation using a commercial software. Europace. Published 16 June 2025. doi:10.1093/europace/euaf122

Composed by AI from the published abstract and checked against it. How Briefs are made →

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