Arrhythmias & electrophysiology

Excellent Outcomes After First-Line Ablation in Post-MI Patients With Tolerated Ventricular Tachycardia (VT) and Left Ventricular Ejection Fraction (LVEF) >35%

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

Post-MI patients with LVEF >35%, tolerated VT, and noninducibility after ablation have an excellent prognosis.

Study context

Population
Post-MI patients without prior implantable cardioverter-defibrillator (ICD) undergoing VT ablation, single centre, 2009–2022
Participants
86 patients
Exposure
Outcomes after VT ablation by LVEF, VT tolerance and acute ablation outcome (noninducible vs inducible)
  • Noninduciblen = 37
  • Induciblen = 14reference
Outcome
SCD and VT recurrence
Follow-up
Median 40 months (Q1-Q3: 24-70 months)
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

GroupSudden cardiac death (SCD)VT recurrence
Noninducible00
Inducible029%

Sudden cardiac death (SCD)

Noninducible0
Inducible0

VT recurrence

Noninducible0
Inducible29%

Observational data: associations, not effects.

Further findings

VT recurrence and mortality, all patients · median follow-up 40 months

VT recurrence
10 of 86
Overall mortality
27%
Sudden death (patient with ICD)
1

Noninducibility after ablation (LVEF >35%, tolerated VT)

Rendered noninducible
37 (73%) of 51

Original publication

Excellent Outcomes After First-Line Ablation in Post-MI Patients With Tolerated VT and LVEF >35%. JACC Clin Electrophysiol. Published 21 August 2024. doi:10.1016/j.jacep.2024.06.027

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