Arrhythmias & electrophysiology
Incidence and type of recurrent ventricular arrhythmia in patients with arrhythmic mitral valve prolapse and implantable cardioverter defibrillator for secondary prevention
Authors' conclusion
Arrhythmic MVP patients with ICDs for secondary prevention exhibit a high risk of recurrent arrhythmias, with recurrences in the form of polymorphic VA occurring in more than half of the cases.
Study context
- Population
- Arrhythmic mitral valve prolapse (MVP) patients with an implantable cardioverter-defibrillator (ICD) implanted for secondary prevention
- Participants
- 166 patients · 9 studies
- Outcome
- Incidence of appropriate ICD therapies and type of arrhythmia recurrence
Pooled result
As reported in the abstract
weighted mean follow-up 4.9 ± 3.1 years
Recurrence of VA
34.9%
95% CI 28.1–42.5
Pooled incidence of appropriate ICD therapies
8.1 per 100 person-years
95% CI 5.6–10.5, I2: 11.7%
Recurrences as VF or polymorphic ventricular tachycardia (VT) (remainder monomorphic VT)
53.8%
95% CI 44.3–63.0%
Further pooled results
Shock therapy among VA episodes
- 65 of 67 episodes required shock (7 studies)
- 97.0% (95% CI 89.6-99.6%)
Original publication
Incidence and type of recurrent ventricular arrhythmia in patients with arrhythmic mitral valve prolapse and implantable cardioverter defibrillator for secondary prevention. Europace. Published 15 May 2026. doi:10.
Summarised from the published abstract; every number is checked against it