Arrhythmias & electrophysiology
Expedited loading with intravenous sotalol is safe and feasible—primary results of the Prospective Evaluation Analysis and Kinetics of intravenous (IV) Sotalol (PEAKS) Registry
Authors' conclusion
IV sotalol loading is safe and feasible for atrial arrhythmias, with low rates of adverse events, and yields shorter hospitalizations.
Study context
- Population
- Patients undergoing elective IV sotalol load for atrial arrhythmiasconsecutively enrolled
- Participants
- 167 patients
- Outcome
- Adverse arrhythmia events, efficacy and length of stay
- Follow-up
- Hospital admission until first outpatient
Methodological detailsmulticenter, consecutive enrolment
- Multicenter
- Consecutive enrolment
Main finding
As reported in the abstract
Mean length of stay (days)
1.1
Discharged within 1 night
95%
n = 159
Observational data: associations, not effects.
Safety
Sotalol infusion stopped for bradycardia or hypotension
- Patients with infusion stopped
- 2
Sotalol discontinued before discharge
- Patients discontinued
- 6
- QTc prolongation
- 3
- Bradycardia
- 1
- Recurrent atrial arrhythmia
- 2
Original publication
Expedited loading with intravenous sotalol is safe and feasible—primary results of the Prospective Evaluation Analysis and Kinetics of IV Sotalol (PEAKS) Registry. Heart Rhythm. Published 28 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →