Arrhythmias & electrophysiology
Home Sotalol Initiation for the Management of Atrial and Ventricular Arrhythmias Using Remote Electrocardiographic Monitoring
Authors' conclusion
Outpatient initiation of sotalol through a protocol-driven, pharmacist-led antiarrhythmic clinic is feasible and safe, with high adherence rates in a diverse range of patients using personal remote ECG.
Study context
- Population
- Patients initiating sotalol for atrial and ventricular arrhythmias, September 1, 2020 to June 16, 2023
- Participants
- 263 vs 28
- Exposure
- Outpatient sotalol initiation with remote electrocardiographic (ECG) vs inpatient initiation
- Outpatientn = 263
- Inpatientn = 28reference
- Outcome
- Safety, feasibility and patient adherence to outpatient sotalol initiation
Methodological detailsage- and sex-matched comparison cohort, pharmacist-led antiarrhythmic clinic
- Age- and sex-matched comparison cohort
- Pharmacist-led antiarrhythmic clinic
Main finding
As reported in the abstract
3-day initiation
| Group | Value | Completed ECG day 1 | Completed ECG day 3 |
|---|---|---|---|
| Outpatient | 98.9% | 258 (98.1%) | 240 (91.3%) |
Outpatient
Value98.9%
Completed ECG day 1258 (98.1%)
Completed ECG day 3240 (91.3%)
- Completed 3-day outpatient initiation
- 260 of 263
Observational data: associations, not effects.
Further findings
Sotalol discontinuation · within 30 days
P > 0.90
- Final dose category (low, moderate, high) · end of initiation · similar proportions
- P = 0.5
Safety
- Stopped sotalol for symptomatic bradycardia; death (outpatient) · 90-day follow-up
- 6.5% · 17 of 263
QTc prolongation (outpatient) · postinitiation
- No significant QTc interval prolongation
Original publication
Home Sotalol Initiation for the Management of Atrial and Ventricular Arrhythmias Using Remote Electrocardiographic Monitoring. JACC Clin Electrophysiol. Published 20 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →