Heart failure & cardiomyopathies

Extreme phenotypes of the female athlete’s heart: a sports-specific cardiac magnetic resonance imaging study

Eur Heart J Cardiovasc ImagingPublished Cross-sectional, multicentre study

Authors' conclusion

Female elite athletes, particularly endurance-trained athletes, display EICR marked by increased ventricular volumes, without prominent increases in LVM or wall thickness.

Study context

Population
Female elite athletesfemale elite athletes (median age 25 years, median 18 h training/week, 97% Caucasian)
Participants
173 athletes
Exposure
Cardiac magnetic resonance imaging (MRI) metrics to female reference values, stratified by ESC sports classification (endurance, mixed, power/skill)
Outcome
LV EDV/BSA and LVM/BSA
Methodological detailscontrast-enhanced cardiac MRI
  • Contrast-enhanced cardiac MRI

Main finding

As reported in the abstract

Mean LV end-diastolic volume (EDV)/body surface area (BSA)

108 ± 13 mL/m²

Mean LV mass (LVM)/BSA

50 ± 10 g/m²

Observational data: associations, not effects.

Further findings

OutcomeEnduranceMixedPower/skill
LVM/BSA by sports classification vs general populationmean 53 ± 11 g/m²mean 48 ± 9 g/m²— not stated in the abstract
Biventricular EDV/BSA
LV111 (101-118)109 (103-119)99 (92-105)
RV112 (105-124)110 (103-118)101 (95-104)

— not stated in the abstract

  • LVM/LV EDV ratio: female elite athletes 0.5 ± 0.1
  • LVM/LV EDV ratio: general population 0.7 ± 0.1 g/mL
  • LVM/LV EDV ratio: lower in athletes; P < 0.001
  • LVM/BSA by sports classification vs general population: general population mean 45 ± 7 g/m²
  • LVM/BSA by sports classification vs general population: mixed vs general population P = 0.021
  • LVM/BSA by sports classification vs general population: endurance vs general population P < 0.001
  • LVM/BSA by sports classification vs general population: endurance surpassing mixed P = 0.004
  • Biventricular EDV/BSA: greater in mixed and endurance vs power/skill; P < 0.001

Remodelling pattern

Isolated LV EDV increases
71%
LVM increases (commonly coincided with LV EDV increases)
18%

Maximum wall thickness > 11 mm

Maximum wall thickness > 11 mm (rare)
2%

Tissue characterisation

Global T1 time
968 ± 22 ms
Extracellular volume
25 ± 4%

Original publication

Extreme phenotypes of the female athlete’s heart: a sports-specific cardiac magnetic resonance imaging study. Eur Heart J Cardiovasc Imaging. Published 2 June 2025. doi:10.1093/ehjci/jeaf111

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