Arrhythmias & electrophysiology
Feasibility and midterm effectiveness of focal pulsed field ablation for ventricular arrhythmias
Authors' conclusion
Focal PFA exhibited satisfactory acute effectiveness for PVC and VT, but favorable clinical effectiveness was retained only in PVC patients. More data are needed to establish lesion durability, safety, and limitations of PFA in ventricular tissue.
Study context
- Population
- Patients scheduled for ablation of premature ventricular complexes (PVCs) or ventricular tachycardia (VT)all patients scheduled for ablation · PVCs 24 · VT 11
- Participants
- 35 patients
- Comparison
- PVCs vs VT
- PVCsn = 24
- VTn = 11
- Outcome
- Previously failed radiofrequency ablation
Main finding
As reported in the abstract
Patients with previously failed radiofrequency ablation
11
31%
Further findings
Success · mean follow-up of 288 ± 149 days
| Outcome | PVCs | VT | |
|---|---|---|---|
| Origin and aetiology | originated from the outflow tracts 58% | caused by ischemic cardiomyopathy 55% | |
| PFA delivered combined endocardially and through the cardiac venous system | 25% | Not reported in the abstract | VT: not reported in the abstract |
| Reablation during follow-up | 1 events | 4 events |
- Reablation during follow-up — Patients reablated
- 5
Procedure time
- Average procedure time
- 187 ± 59 minutes
Acute procedural success
- Acute procedural success
- 91%
Safety
- Minor complications
- 7 (20%)
- Major complications
- 2 (6%)
- Transient conduction system blocks related to pulsed field delivery
- 2
- Stroke
- 1
- Minor stroke
- 1
Original publication
Feasibility and midterm effectiveness of focal pulsed field ablation for ventricular arrhythmias. Heart Rhythm. Published 10 February 2025. doi:10.
Summarised from the published abstract; every number is checked against it