Arrhythmias & electrophysiology
Feasibility and safety of single-pulse ablation in 20 patients with atrial fibrillation
Authors' conclusion
Acute electrical PVI could be achieved safely and rapidly. Acute silent cerebral lesions were detected in 3 of 20 patients (15%) and may be caused by ablation or changes of therapeutic and diagnostic catheters over a single transseptal access.
Study context
- Population
- Patients with symptomatic AF undergoing pulmonary vein isolation
- Participants
- 20 patients
- Outcome
- Safety of single-pulse ablation for PVI
Main finding
As reported in the abstract
All pulmonary veins successfully isolated
20 patients
Irreversible electroporation (IRE) applications per patient
11.8 ± 1.4 (mean)
PV reconnection during adenosine testing; reisolated with 2 additional IRE pulses
1
Periprocedural complications
0
Observational data: associations, not effects.
Safety
Silent cerebral lesions (brain magnetic resonance imaging (MRI)) · day 1 after ablation
- Punctate asymptomatic lesions, 3 of 20 patients
- 15%
- At follow-up MRI, the lesion disappeared in 1 patient; 1 lesion persisted in the other 2 patients
Asymptomatic esophageal lesion (esophagoscopy) · day 1
- Asymptomatic esophageal lesion, 1 of 20 patients
- 5%
- Resolved completely at repeat esophagoscopy on day 22
Periprocedural complications
- No periprocedural complications observed
Original publication
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