Arrhythmias & electrophysiology
Feasibility of atrial linear ablation using a lattice tip catheter that toggles between radiofrequency and pulsed-field energy under deep sedation
Authors' conclusion
This preliminary clinical study demonstrates feasibility and safety of bidirectional block of linear lesions using a lattice tip catheter under deep sedation.
Study context
- Population
- Patients undergoing atrial fibrillation (AF) ablation including linear lesion ablation for atrial tachyarrhythmia with a lattice tip catheter (radiofrequency/pulsed-field), Germany
- Participants
- 55 patients
- Exposure
- Linear ablation under deep sedation vs general anesthesia (GA)
- Deep sedationn = 40
- GAn = 15reference
- Outcome
- Bidirectional block of linear lesions
Methodological detailstwo high-volume AF centres
- Two high-volume AF centres
Main finding
As reported in the abstract
| Group | Value | Lesions blocked |
|---|---|---|
| GA | 21 events | 21 of 21 |
| Deep sedation | 97% | 74 of 76 |
Value
GA21 events
Deep sedation97%
Lesions blocked
GA21 of 21
Deep sedation74 of 76
- Deep sedation vs GA: P = 1.000
Observational data: associations, not effects.
Further findings
Bidirectional block by lesion type
- Roof line
- 41 of 41 (100%)
- Posterior wall isolation
- 4 of 4 (100%)
- Anterior mitral isthmus line (GA vs deep sedation)
- 5 of 5 (100%) vs 24 of 25 (96%)
- Posterior mitral isthmus line (GA vs deep sedation)
- 1 of 1 (100%) vs 4 of 5 (80%)
- Cavotricuspid isthmus line
- 15 of 15 (100%)
- Left atrial appendage isolation
- 1
Safety
Overall complications
- Overall complication rate (1 cardiac tamponade)
- 1.8%
- Other procedure-related complications
- 0
Original publication
Feasibility of atrial linear ablation using a lattice tip catheter that toggles between radiofrequency and pulsed-field energy under deep sedation. Heart Rhythm. Published 19 November 2024. doi:10.
Summarised from the published abstract; every number is checked against it