Five-year follow-up of optical coherence tomography (OCT)-guided percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction
Authors' conclusion
Compared with angiography alone, OCT guidance may change reperfusion strategies and lead to better long-term survival in STEMI patients undergoing pPCI.
Study context
- Population
- STEMI patients undergoing primary PCI, January 2017–December 2020
- Participants
- 3,897 patients
- Exposure
- OCT-guided vs angiography-guided primary PCI
- OCT-guidedn = 2,696
- Angiography-guidedn = 1,201reference
- Outcome
- All-cause death
- Follow-up
- Up to 5 years
Methodological detailsmultivariate models, propensity score matching
- Multivariate models
- Propensity score matching
Main finding
As reported in the abstract
All-cause mortality
OCT-guided vs Angiography-guidedHazard ratio (95% CI)P value
Multivariate model 4; P is log-rank
0.689(0.551–0.862)
P < 0.001After propensity score matching
0.707(0.548–0.913)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | OCT-guided | Angiography-guided | HR (95% CI) | P value | |
|---|---|---|---|---|---|
| CV mortality · up to 5 yearsMultivariate model 4; P is log-rank | 8.0% | 14.1% | 0.692 (0.536–0.895) | P < 0.001 | |
| CV mortality · up to 5 yearsAfter propensity score matching | 0.709 (0.526–0.955) | ||||
| 0.512Hazard ratio (log scale) |
Stenting during pPCI
P < 0.001
Original publication
Five-year follow-up of OCT-guided percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction. EuroIntervention. Published 5 August 2024. doi:10.
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