Impact of morphofunctional assessment with quantitative flow ratio and optical coherence tomography in patients with acute coronary syndromes
Authors' conclusion
Combining post-PCI OCT and QFR evaluation may enhance risk stratification for ACS patients after successful PCI, particularly in predicting subsequent TVF.
Study context
- Population
- Acute coronary syndrome (ACS) patients who had undergone optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI)
- Participants
- 298 patients
- Exposure
- Post-PCI morphofunctional assessment for risk stratification
- Outcome
- TVF (cardiac death, target vessel-related MI, ischaemia-driven target vessel revascularisation)
- Follow-up
- Median 990 days
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
TVF
Patients with target vessel failure (TVF)
42
TVF incidence, thin-cap fibroatheroma (TCFA) in non-culprit segment (NCS) and low post-PCI quantitative flow ratio (QFR) (significantly higher than other subgroups)
75%
TVF incidence, TCFA in NCS and high ΔQFRNCS (significantly higher than other subgroups)
86%
Observational data: associations, not effects.
Further findings
Identification of TVF cases
- Adding TCFA in NCS, post-PCI QFR and ΔQFRNCS to traditional risk factors significantly enhanced identification of TVF
Original publication
Impact of morphofunctional assessment with quantitative flow ratio and optical coherence tomography in patients with acute coronary syndromes. EuroIntervention. Published 5 August 2024. doi:10.
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