Arrhythmias & electrophysiology
Frequency of Electrocardiogram-Defined Cardiac Conduction Disorders in a Multi-Institutional Primary Care Cohort
Authors' conclusion
Cardiac conduction disorders are common in a primary care population, especially among older individuals with cardiovascular risk factors.
Study context
- Population
- Adults receiving longitudinal primary care 2001–2019 with ≥1 12-lead electrocardiogram (ECG) before and ≥1 during follow-up119,926 in incidence analysis
- Participants
- 189,163 adults
- Exposure
- Men vs Women
- Outcome
- Prevalence and incidence of ECG-defined cardiac conduction disorders
Methodological detailsmulti-institutional
- Multi-institutional
Main finding
As reported in the abstract
median 10 years (Q1, Q3: 6, 15 years) follow-up
| Group | Value | Incidence |
|---|---|---|
| Men | 27% | 8.78 events/1,000 person-years |
| Women | 15% | 4.34 events/1,000 person-years |
Value
Men27%
Women15%
Incidence
Men8.78 events/1,000 person-years
Women4.34 events/1,000 person-years
- Men vs Women: P < 0.05 — incidence
- Incident conduction system abnormality (of 119,926)
- 6,802
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Clinical factors associated with incident conduction disorders (multivariable)Older age (per 5-year increase) | 1.25 (1.24–1.26) | |
| 0.512Hazard ratio (log scale) |
Clinical factors associated with incident conduction disorders (multivariable)
| HR (95% CI) | ||
|---|---|---|
| MI | 1.39 (1.26–1.54) | |
| 0.512Hazard ratio (log scale) |
Original publication
Frequency of Electrocardiogram-Defined Cardiac Conduction Disorders in a Multi-Institutional Primary Care Cohort. JACC Adv. Published 24 May 2024. doi:10.
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