Valvular & structural heart disease
GLIDE Score is associated with procedural success in patients undergoing direct transcatheter tricuspid valve annuloplasty
Authors' conclusion
The GLIDE Score reliably identifies patients with a high likelihood of achieving procedural success after TTVA. Incorporating annular diameters may further improve predictive accuracy and guide treatment selection in patients undergoing transcatheter tricuspid valve repair.
Study context
- Population
- Patients who underwent transcatheter tricuspid valve annuloplasty (TTVA) between 2018 and 2023 at two tertiary German centresconsecutive patients in the main cohort, external validation cohort n = 86 · Main cohort 204 · External validation cohort 86
- Participants
- 204 patients
- Predictors
- GLIDE Score (septolateral gap, predominant jet location, image quality, chordal structure density, and en-face jet morphology), assessed using preprocedural transoesophageal echocardiograms; modified GLIDE Score excluding chordal structure density and including anteroseptal and bicommissural annular diameters
- Predicted outcome
- Procedural success after TTVA
Methodological detailsexternal validation cohort
- External validation cohort
Model performance
As reported in the abstract
Area under the curve
Modified GLIDE Score, main cohort
0.84
Original GLIDE Score, main cohort
0.79(95% CI: 0.72-0.85)
Modified GLIDE Score, external validation cohort (n = 86)
0.76
Further findings
Residual TR ≤ I by GLIDE Score
Procedural outcomes
- Residual tricuspid regurgitation (TR) grade ≤ I
- 44.6%
- TR reduction of ≥2 grades
- 83.7%
- Residual TR grade ≤ II
- 72.8%
Association of lower GLIDE Scores with procedural outcomes
- Lower GLIDE Scores associated with higher rates of residual TR ≤ I and residual TR ≤ II
- P < 0.001
- Lower GLIDE Scores associated with higher rates of TR reduction of ≥2 grades
- P = 0.001
Procedural outcomes, adjusted for baseline TR grade
- GLIDE Score still independently associated with procedural outcomes
- After adjustment for baseline TR grade
Original publication
GLIDE Score is associated with procedural success in patients undergoing direct transcatheter tricuspid valve annuloplasty. Eur Heart J Cardiovasc Imaging. Published 15 December 2025. doi:10.
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