Prevention & lipids

Global and Regional Cardiovascular Mortality Attributable to Nonoptimal Temperatures Over Time

J Am Coll CardiolPublished Multi-country time-series study with meta-regression

Authors' conclusion

Nonoptimal temperatures substantially contribute to cardiovascular mortality, with heterogeneous spatiotemporal patterns.

Study context

Population
Daily CV deaths and temperature data from 32 countries, extrapolated globally32 countries
Outcome
Global CV mortality burden attributable to nonoptimal temperatures
Methodological detailsglobal burden assessment, 3-stage analysis, 32 countries, global grid 55 km × 55 km, 2000–2019
  • Global burden assessment
  • 3-stage analysis
  • 32 countries
  • Global grid 55 km × 55 km
  • 2000–2019

Main finding

As reported in the abstract

Annual CV deaths attributable to nonoptimal temperatures
Annual CV deaths associated with nonoptimal temperatures
1,801,513 (95% empirical CI 1,526,632-2,202,831)
Share of total CV mortality
8.86% (95% empirical CI 7.51%-12.32%)
Deaths per 100,000 population
26
Cold-related share
8.20% (95% empirical CI 6.74%-11.57%)
Heat-related share
0.66% (95% empirical CI 0.49%-0.98%)

Further findings

Regional variation

Highest excess mortality rates in Central Asia and Eastern Europe

Temporal trends · 2000 to 2019

Cold-related excess death ratios decreased, heat-related increased; overall decline in temperature-related deaths
Greatest reduction in Southeastern Asia, Sub-Saharan Africa and Oceania; increase in Southern Asia
Fluctuating patterns in the Americas and several regions in Asia and Europe

Original publication

Global and Regional Cardiovascular Mortality Attributable to Nonoptimal Temperatures Over Time. J Am Coll Cardiol. Published 11 June 2024. doi:10.1016/j.jacc.2024.03.425

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