Heart failure & cardiomyopathies

Global Trends in Heart Failure from 1990 to 2019: An Age-Period-Cohort Analysis from the Global Burden of Disease Study

ESC Heart FailPublished Secondary analysis of the Global Burden of Disease study

Authors' conclusion

This study offers valuable insights into the global burden of HF, considering factors such as population aging, regional disparities, sex differences and aetiological variations.

Study context

Population
Global population, 1990–2019, by sex and Socio-demographic Index (SDI)
Primary endpoint
HF prevalence and years lived with disability (YLDs) trends
Follow-up
1990–2019
Methodological detailsage-period-cohort analysis, Joinpoint regression, stratified by sex and SDI
  • Age-period-cohort analysis
  • Joinpoint regression
  • Stratified by sex and SDI

Primary result

As reported in the abstract

Global HF prevalence

Increase in global heart failure (HF) prevalence (95% uncertainty interval 99.3% to 114.3%)

106.3%

HF cases in 2019

56.2 million

Average annual percentage change, prevalence

−0.26%

Average annual percentage change, years lived with disability (YLDs)

−0.25%

Further findings

Causes of HF

Ischaemic heart disease and hypertensive heart disease the most rapidly increasing and main contributing causes, varying across countries

Original publication

Global Trends in Heart Failure from 1990 to 2019: An Age-Period-Cohort Analysis from the Global Burden of Disease Study. ESC Heart Fail. Published 27 June 2024. doi:10.1002/ehf2.14915

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