Global Trends in Ischemic Heart Disease-Related Mortality From 2000 to 2019
Authors' conclusion
While global IHD mortality has declined from 2000 to 2019, disparities by geographic region and sex persist. Implementing targeted health awareness programs and collaborative global health efforts are crucial for addressing these inequalities.
Study context
- Population
- Ischemic heart disease (IHD) mortality data from 105 countries, 2000 to 2019
- Participants
- 105 countries
- Exposure
- Regional and sex-specific trends in CMR and ASMR
- Outcome
- Global CMR
- Follow-up
- 2000 to 2019
Methodological detailsjoinpoint regression, stratified analyses of CMR and ASMR
- Joinpoint regression
- Stratified analyses of CMR and ASMR
Main finding
As reported in the abstract
CMR 2000
138 per 100,000
95% CI 131–145
CMR 2019
106 per 100,000
95% CI 102–114
Average annual percentage change (AAPC)
−1.79, 95% CI: −1.93 to −1.66
Observational data: associations, not effects.
Further findings
Global ASMR · 2000 to 2019
- ASMR 2000
- 104 per 100,000 (95% CI: 99-108)
- ASMR 2019
- 65.5 (95% CI: 62-69)
- AAPC
- −2.16, 95% CI: −2.13 to −2.20
Regional CMR
- Crude mortality rates (CMRs) decreased in Oceania, Europe, and North America, while they rose in Asia, Africa, and Central and South America
Regional ASMR
- Africa AAPC
- 1.33, 95% CI: 1.30-1.36
- Age-standardized mortality rates (ASMRs) declined worldwide except in Africa
Mortality by sex
- Males showed higher mortality than females, but both sexes demonstrated decreasing trends, with males having a steeper decline
Mortality by age group across regions
- Africa showed an upward trend, while other regions demonstrated declines
Original publication
Global Trends in Ischemic Heart Disease-Related Mortality From 2000 to 2019. JACC Adv. Published 19 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →